Peripheral Neuropathy Causes

Peripheral neuropathy has many different causes. Some people inherit the disorder from their parents. Others develop it because of an injury or another disorder.

In many cases, a different type of problem, such as a kidney condition or a hormone imbalance, leads to peripheral neuropathy. One of the most common causes of peripheral neuropathy in the U.S. is diabetes.

Peripheral Neuropathy Types

There are more than 100 types of peripheral neuropathy, each with its own set of symptoms and prognosis. To help doctors classify them, they are often broken down into the following categories:

Motor neuropathy

This is damage to the nerves that control muscles and movement in the body, such as moving your hands and arms or talking.

Sensory neuropathy

This is damage to the nerves that control muscles and movement in the body, such as moving your hands and arms or talking.

Autonomic nerve neuropathy

Autonomic nerves control functions that you are not conscious of, such as breathing and heartbeat. Damage to these nerves can be serious.

Combination neuropathies

You may have a mix of 2 or 3 of these other types of neuropathies, such as a sensory-motor neuropathy.

Peripheral Neuropathy Symptoms

The symptoms of peripheral neuropathy vary based on the type that you have and what part of the body is affected. Symptoms can range from tingling or numbness in a certain body part to more serious effects such as burning pain or paralysis.

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Muscle weakness

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Cramps

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Muscle twitching

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Loss of muscle and bone

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Changes in skin, hair, or nails

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Numbness

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Loss of sensation or feeling in body parts

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Loss of balance or other functions as a side effect of the loss of feeling in the legs, arms, or other body parts

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Emotional disturbances

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Sleep disruptions

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Loss of pain or sensation that can put you at risk, such as not feeling an impending heart attack or limb pain

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Inability to sweat properly, leading to heat intolerance

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Loss of bladder control, leading to infection or incontinence

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Dizziness, lightheadedness, or fainting because of a loss of control over blood pressure

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Diarrhea, constipation, or incontinence related to nerve damage in the intestines or digestive tract

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Trouble eating or swallowing

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Life-threatening symptoms, such as difficulty breathing or irregular heartbeat